The Anti 3R-Tau, Rat Monoclonal Antibody(2A1-1F4) from FUJIFILM Wako Chemicals U.S.A. Corp is a Rat Monoclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The Anti 3R-Tau, Rat Monoclonal Antibody(2A1-1F4) has been validated for the following applications: Precipitation, Immunoprecipitation, and Western Blot.
Description
This product is an antibody that specifically recognizes 3R-Tau.Tau is one type of microtubule-binding protein that is primarily expressed within the neurons of the central nervous system and is involved in the modulation of microtubule stability. In Alzheimer's disease, the formation of neurofibrillary tangles with accumulated phosphorylated Tau proteins is known to occur. Since correlations between the occurrence frequency of neurofibrillary tangles and severity of dementia were reported, neurofibrillary tangles have been studied for determination of the causes and development of therapeutic agents for Alzheimer's disease.Tau is classified into 3R-Tau and 4R-Tau which has 3 and 4 microtube association domains, respectively